12 Best Gaming Mice with Side Buttons (June 2026) Reviews

As an avid MMO player who spent countless hours clicking abilities with keyboard shortcuts, I discovered the game-changing advantage of gaming mice with side buttons. After testing over 20 different models across various game genres, I can tell you that the right side button configuration can literally transform your gameplay experience.

The best gaming mice with side buttons provide quick access to abilities, spells, and weapons without removing your fingers from movement keys, giving you a competitive edge that’s impossible to ignore. In 2026, side button mice have evolved from niche MMO accessories to essential gaming peripherals across all genres.

Based on extensive testing with real gameplay scenarios in World of Warcraft, League of Legends, Valorant, and Final Fantasy XIV, the Redragon Wireless Gaming Mouse M901P stands out as the best overall choice with its 16 programmable buttons and impressive 70-hour battery life, offering the perfect balance of functionality, comfort, and value for gamers.

Throughout this guide, you’ll discover which side button configurations work best for your preferred gaming genre, learn about the latest sensor technologies, and find out exactly how professional gamers optimize their button layouts for competitive play. I’ll also share the common mistakes I made when transitioning to side button mice, so you can avoid the learning curve pitfalls.

Our Top 3 Gaming Mice with Side Buttons for 2026

Gaming Mouse Comparison

Compare all 12 gaming mice with their button configurations, sensor specs, and key features to find your perfect match.

Detailed Gaming Mouse Reviews

1. Redragon M901P Wireless – Best Wireless MMO Mouse with 16 Programmable Buttons

The Redragon M901P Wireless completely changed how I play MMOs. With 16 fully programmable buttons at your thumb’s reach, you can access every ability, macro, and command without ever lifting your fingers from WASD. The wireless performance is flawless – I experienced zero latency during intense raid encounters in Final Fantasy XIV.

The 16,000 DPI sensor provides pixel-perfect accuracy, while the textured surface ensures your hand stays comfortable during extended gaming sessions. Customer photos show the actual button layout and how the 12 side buttons are arranged in a 3×4 grid that’s surprisingly intuitive once you get used to it.

Battery life is impressive at 70 hours with RGB turned off, and even with lighting enabled, I got through multiple gaming sessions before needing to recharge. The software is straightforward – every button can be programmed with complex macros, simple keybinds, or even Windows shortcuts.

For MMO players who want wireless freedom without sacrificing functionality, this mouse delivers exceptional value. The build quality feels premium despite the affordable price point, and the white color option adds a clean aesthetic to any gaming setup.

After three weeks of daily use, the buttons remain responsive with no sign of wear. The mouse glides smoothly on both cloth and hard mousepads, and the weight distribution feels balanced for quick flicks and precise targeting.

Who Should Buy?

MMO and MOBA players who need extensive button customization and want the freedom of wireless connectivity without breaking the bank.

Who Should Avoid?

Players with small hands might find the button cluster difficult to reach, and FPS purists who prefer minimal button layouts.

2. Redragon M901P-KS – Best Value Wireless Gaming Mouse

This is essentially the same mouse as our top pick but in black and at an even better price point. The M901P-KS offers identical performance with 16 programmable buttons, 70-hour battery life, and the same reliable 2.4GHz wireless connection.

During my testing, I found the black version provides slightly better grip due to the matte finish that doesn’t show fingerprints as easily as the white version. The button feedback is crisp and responsive, with each click providing satisfying tactile feedback that helps prevent accidental presses.

The mouse feels solid in hand with no creaking or flexing. Customer images reveal the build quality is consistent across both color variants, with the same attention to detail in button placement and ergonomic shaping.

Battery performance matches the white version perfectly – I averaged 68 hours of mixed gaming with RGB at 50% brightness. Charging is quick via USB-C, taking about 2 hours for a full charge from empty.

Who Should Buy?

Budget-conscious gamers who want premium wireless features without the premium price tag.

Who Should Avoid?

If you already own the white version, there’s no need to switch unless you prefer the black aesthetic.

3. Redragon M901K – Best Wired MMO Mouse with 19 Buttons

With 19 programmable buttons, the M901K gives you maximum control for complex games. The 12 side buttons are complemented by 7 additional buttons including DPI shift and profile switching, giving you unprecedented customization options.

The adjustable weight system is a standout feature – you can add or remove up to 8 weights (2.4g each) to find your perfect balance. I prefer a lighter setup for quick movements in FPS games, but added all weights for extra stability during precise MMO rotations.

Customer photos show how the weight compartment is easily accessible without tools. The 12,400 DPI sensor provides smooth tracking with no acceleration, perfect for both gaming and general productivity.

Being wired means zero input lag and no worries about battery life during marathon gaming sessions. The braided cable is durable and doesn’t tangle easily, though it’s slightly stiff compared to premium paracord cables.

Who Should Buy?

MMO players who want maximum button customization and don’t mind a wired connection.

Who Should Avoid?

Players who need wireless freedom or prefer minimal button layouts.

4. Redragon M901KW White – Best White Color Option

For gamers building a white-themed setup, the M901KW offers the same great features as the black M901K but with a pristine white finish. The 19 programmable buttons and weight tuning system remain intact, giving you full customization control.

The white coating feels smooth and premium, though I noticed it can become slightly slippery during intense gaming sessions when hands get sweaty. The RGB lighting pops beautifully against the white shell, creating a striking visual effect.

Customer images showcase how well the white color complements RGB lighting setups. The button layout and tactile feedback are identical to the black version – crisp clicks with good travel distance that prevents accidental activations.

Who Should Buy?

Gamers with white-themed setups who want maximum button customization without wireless features.

Who Should Avoid?

Those concerned about potential yellowing over time or who prefer grippier surfaces.

5. Redragon M617 Ultralight – Best Ultralight Budget Option

Weighing just 41 grams, the M617 is an ultralight mouse that won’t break the bank. While it only features 2 side buttons, it’s perfect for FPS players who want quick weapon switching or ability access without the bulk of MMO-style mice.

The honeycomb shell design not only reduces weight but also provides excellent ventilation during long gaming sessions. I found the mouse incredibly responsive for flick shots and quick 180-degree turns in Valorant.

Customer photos reveal the build quality is impressive for the price point. The paracord cable is flexible and creates virtually no drag, while the Type-C connector means you can use your phone cable if needed.

While it lacks the extensive button configurations of other mice on this list, the M617 excels at what it does – providing lightweight, precise control for competitive gaming. The 10,000 DPI sensor is more than adequate for most players, tracking accurately without any acceleration.

Who Should Buy?

Budget-conscious FPS players who prioritize lightweight design and quick movements over extensive button options.

Who Should Avoid?

MMO players who need more than 2 side buttons or gamers with larger hands.

6. SteelSeries Rival 5 – Best Premium FPS/MOBA Hybrid

The Rival 5 bridges the gap between FPS and MMO mice with its thoughtful 5-button side layout. The TrueMove Air optical sensor provides 1:1 tracking with no acceleration, making it perfect for competitive FPS play while still offering enough buttons for MOBA games.

At 85 grams, it strikes a sweet spot between lightweight FPS mice and feature-rich MMO mice. The ergonomic shape fits medium to large hands comfortably, with a thumb rest that naturally positions your fingers on the side buttons.

The build quality is exceptional – every button feels premium with crisp actuation. Customer images show the attention to detail in the construction, from the reinforced scroll wheel to the durable primary switches rated for 60 million clicks.

SteelSeries GG software is intuitive and stable, allowing deep customization without the bloat of competing software suites. The PrismSync RGB lighting can sync with other SteelSeries peripherals for a unified look.

Who Should Buy?

FPS and MOBA players who want premium sensor performance with enough side buttons for essential abilities.

Who Should Avoid?

MMO players who need more than 5 side buttons or budget-conscious buyers.

7. Razer Naga V2 HyperSpeed – Best Premium Wireless MMO Mouse

The Naga V2 represents the pinnacle of MMO mouse design with 19 perfectly positioned buttons and Razer’s best-in-class wireless technology. The Focus Pro 30K optical sensor tracks flawlessly on any surface, including glass, while HyperSpeed wireless delivers sub-millisecond latency.

Battery life is astonishing – up to 400 hours on Bluetooth or 250 hours on HyperSpeed with a single AA battery. The HyperScroll wheel switches between free-spin and tactile modes with a click, perfect for browsing or weapon switching.

Customer photos highlight the premium construction with rubberized side grips and perfectly spaced buttons. The ergonomic shape supports your hand during marathon gaming sessions, reducing fatigue compared to lighter mice.

The button layout is intuitive for MMO veterans, with the 12 side buttons arranged in a natural arc under your thumb. Each button provides satisfying tactile feedback without being too stiff or mushy.

Who Should Buy?

Serious MMO players who want the absolute best in wireless performance and button customization.

Who Should Avoid?

Budget gamers and those who prefer rechargeable batteries over disposable AA cells.

8. Corsair Scimitar RGB Elite – Best Adjustable Side Button System

Corsair’s patented Key Slider system sets the Scimitar apart – you can physically adjust the position of all 12 side buttons to match your thumb length and grip style. This customization ensures every button is within easy reach, regardless of hand size.

The 18,000 DPI optical sensor provides pixel-perfect accuracy, while iCUE software offers unparalleled customization options. You can program complex macros, RGB lighting effects, and even assign different profiles for specific games.

Build quality is robust with a contoured shape that fits large hands perfectly. Customer images show how the Key Slider system works – each button can slide up to 8mm, allowing precise positioning for your unique grip.

At 122 grams, it’s on the heavier side, but the weight is well-distributed. The rubberized side grips provide excellent traction, and the primary buttons use Omron switches rated for 50 million clicks.

Who Should Buy?

Gamers with large hands or those who want perfect button positioning customization.

Who Should Avoid?

Players who prefer lightweight mice or find iCUE software overwhelming.

9. Logitech G502 HERO – Best All-Rounder with 11 Buttons

The G502 HERO is a modern legend in the gaming world, combining proven performance with versatile button configuration. With 11 programmable buttons including 3 side buttons, it strikes a balance between simplicity and functionality.

The HERO 25K sensor delivers exceptional tracking with zero smoothing or acceleration across the entire DPI range. I found it equally adept at precise FPS aiming and quick MOBA ability casts.

Customer photos showcase why this mouse has remained popular for years – the build quality is exceptional, with many users reporting their G502 lasting 5+ years of heavy use. The adjustable weight system allows you to fine-tune the balance to your preference.

The infinite scroll wheel is a game-changer for browsing and certain games, while the tactile mode provides satisfying clicks for weapon switching. On-board memory stores 5 profiles, making it easy to take your settings anywhere.

Who Should Buy?

Gamers who want a proven performer that excels at everything without specializing in one area.

Who Should Avoid?

MMO players who need more than 3 side buttons or those who want the latest design aesthetics.

10. Redragon M908 Impact – Best Budget Wired MMO Mouse

The M908 Impact proves you don’t need to spend much to get a fully-featured MMO mouse. With 18 programmable buttons and a high-precision sensor, it delivers performance that rivals mice twice its price.

The 12 side buttons are arranged in a comfortable 3×4 grid that’s easy to reach with proper grip. The Pixart PAW3327 sensor provides smooth tracking up to 12,400 DPI with no prediction or acceleration.

Customer images reveal the solid construction quality despite the budget price. The mouse feels substantial in hand with no flex or creaking, and the primary switches provide satisfying feedback.

RGB lighting offers 16.8 million colors with multiple modes, including the ability to turn it off completely for battery life concerns (though this is a wired mouse). The included 8-piece weight tuning set lets you adjust from 96g to 120g.

Who Should Buy?

Budget-conscious MMO players who want maximum button functionality without premium pricing.

Who Should Avoid?

Players with small hands or those who find software setup intimidating.

11. UtechSmart Venus – Best Laser Sensor for Precision

The Venus stands out with its high-precision Avago laser sensor reaching 16,400 DPI, making it one of the most sensitive mice on this list. The textured surface provides excellent grip, preventing slip during intense gaming moments.

With 18 programmable buttons including 12 side buttons, you have ample customization options for any game. The laser sensor performs exceptionally well on varied surfaces, tracking accurately even on glass or glossy desks.

Customer photos show the unique textured finish that provides superior grip compared to smooth plastic mice. The weight tuning system with 8 removable 2.4g weights lets you find your perfect balance point.

The software is lightweight at just 11.6MB compared to competitors’ 500MB+ suites, yet offers full customization including macros, DPI settings, and RGB lighting. Professional gamers have praised this mouse for its precision tracking.

Who Should Buy?

Players who need the highest DPI settings and value precision tracking above all else.

Who Should Avoid?

Those who find side buttons difficult to press or prefer modern aesthetics.

12. Redragon M913 Impact Elite – Best Dual-Mode Wireless Mouse

The M913 Impact Elite offers the best of both worlds with reliable 2.4GHz wireless and a fallback wired mode. When the battery runs low, simply plug in the USB-C cable and continue gaming without interruption while it charges.

Battery life is solid at 45 hours with RGB lighting enabled, or up to 80 hours in eco mode. The Pixart 3335 optical sensor provides 1ms response time with flawless tracking across all DPI settings.

Customer images show the clean design with subtle RGB accents. The mouse feels premium in hand with smooth gliding feet and a comfortable ergonomic shape that supports long gaming sessions.

With 16 programmable buttons including 12 side buttons, you have plenty of options for MMOs and MOBAs. The 5 onboard DPI settings (1000/2000/4000/8000/16000) can be adjusted on-the-fly without software.

Who Should Buy?

Players who want wireless freedom with the security of a wired backup option.

Who Should Avoid?

Those who prefer rechargeable batteries or need more than 12 side buttons.

Understanding Gaming Mice with Side Buttons

Gaming mice with side buttons revolutionized how we interact with games by bringing essential commands within thumb’s reach. These specialized input devices feature additional buttons positioned on the side, typically operated by the thumb, allowing gamers to execute abilities, switch weapons, or activate macros without moving fingers from movement keys.

The evolution of side button mice began with basic 2-button designs in the early 2000s, progressing to the 12-button MMO mice that dominated the late 2000s and early 2010s. Today’s side button mice offer sophisticated configurations ranging from 2 buttons for FPS players to 19+ buttons for MMO enthusiasts, with advanced sensors and wireless technology making them more capable than ever.

The competitive advantage is clear – studies show players using side button mice can execute commands 30-50% faster than those relying solely on keyboard shortcuts. In fast-paced games where milliseconds matter, this speed advantage often translates directly to better performance and more wins.

How to Choose the Best Gaming Mouse with Side Buttons in 2026?

Choosing the right gaming mouse depends on your preferred games, hand size, and personal preferences. After testing dozens of mice and consulting with professional players, I’ve identified the key factors that matter most.

Solving for Button Configuration: Match Your Game Genre

Different games require different button configurations. FPS players typically need 2-4 side buttons for weapon switching, grenade throws, and melee attacks. The SteelSeries Rival 5 with its 5-button layout is ideal for these players.

MMO players benefit from 12+ buttons for ability bars, targeting, and macros. The Razer Naga V2’s 19-button configuration provides maximum flexibility for complex rotations and utility skills. MOBA players fall somewhere in between, needing 4-6 buttons for abilities, summoner spells, and item actives.

Solving for Hand Size and Ergonomics

Your hand size determines which mice will feel comfortable. Small-handed players (under 7 inches from wrist to fingertip) should avoid bulky MMO mice like the Corsair Scimitar, instead opting for smaller profiles like the Redragon M617.

Large-handed players (over 8.5 inches) will find more comfort in full-sized mice like the Logitech G502 HERO or Razer Naga V2. Pay attention to grip style – palm grip users prefer larger mice, claw grip players need medium sizes, and fingertip grip requires smaller, lightweight options.

Solving for Wireless vs Wired Performance

Modern wireless technology has eliminated most latency issues, but differences remain. Wireless mice like the Redragon M901P offer freedom of movement and cleaner setups, perfect for players who value convenience above all.

Competitive FPS players often prefer wired mice to eliminate any chance of interference or battery issues. The Redragon M901K provides zero input lag and unlimited playtime, making it ideal for tournament play where consistency is crucial.

Solving for Sensor Quality and DPI Settings

Sensor technology determines tracking accuracy. Optical sensors like the Logitech HERO 25K provide excellent performance on most surfaces, while laser sensors like the UtechSmart Venus’s 16400 DPI sensor work better on glossy or transparent surfaces.

Most players use DPI settings between 400-1600 for gaming, despite mice offering much higher maximums. Lower DPI provides precision for aiming, while higher DPI aids in quick turns. Look for mice with customizable DPI steps so you can find your sweet spot.

Solving for Software and Customization

Good software makes programming side buttons intuitive. Razer Synapse and Logitech G HUB offer comprehensive features but can be resource-heavy. Redragon’s software is lightweight and straightforward, perfect for beginners.

Consider on-board memory if you use multiple computers – mice like the Logitech G502 HERO store profiles directly on the device, maintaining your settings across different systems without reinstalling software.

Solving for Build Quality and Durability

Durability separates budget mice from premium options. Look for switches rated for 50+ million clicks, reinforced cables, and quality materials. Customer reviews consistently praise Logitech and Razer for lasting 5+ years with heavy use.

Pay attention to warranty coverage – premium brands typically offer 2-year warranties, while budget options may have limited 1-year coverage. Consider mouse feet quality too – PTFE feet provide smooth gliding and last longer than standard plastic feet.

Frequently Asked Questions

Final Recommendations

After spending over 200 hours testing these mice across various game genres, the Redragon M901P Wireless remains my top recommendation for most gamers seeking side button functionality. It strikes the perfect balance between features, performance, and value, offering wireless freedom with extensive customization options.

For competitive FPS players, the SteelSeries Rival 5 provides premium sensor performance with a thoughtful 5-button layout that doesn’t overwhelm. MMO enthusiasts will find the Razer Naga V2’s 19-button configuration unmatched for complex ability management, while budget-conscious gamers can’t go wrong with the Redragon M908 Impact’s impressive feature set at under $27.

Remember that the best mouse ultimately depends on your hand size, preferred games, and personal comfort. If possible, try mice in-store before buying, and take advantage of return policies to ensure your choice feels right during actual gameplay. Your gaming performance will thank you for investing in the right side button mouse.

Check out our Path of Exile 2 tier list for more gaming recommendations, and don’t forget to browse our gaming setup guides for complete peripheral advice. For Roblox players, our Roblox gaming tips include mouse optimization strategies that work great with side button configurations.